Sleep studies often involve measuring the electrical activity in a person’s brain using electroencephalography.Credit: Getty Scientists once considered sleep to be like a shade getting drawn over a window between the brain and the outside world: when the shade is closed, the brain stops reacting to outside stimuli. A study published on 12 October in…

Abstract Obesity can be categorized as metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUO). However, individuals with MHO are characterized by the absence of metabolic syndrome (MS) and appear to have lower inflammation levels compared to MUO. This study aimed to investigate the association of obesity phenotypes with leptin (LEP) and adiponectin (ADP). According…

Abstract Primary pulmonary sarcoma (PPS) is a rare and poor prognostic malignancy that results from current clinical studies are lacking. Our study aimed to investigate the prognostic factors of PPS and to construct a predictive nomogram that predict the overall survival (OS) rate. We extracted data on patients diagnosed with PPS from 2010 to 2019…

Nobel prizewinners almost never work in isolation. They might be the driving force behind their award-winning discoveries, but a whole host of collaborators, postdoctoral fellows and graduate students helped to realize their vision in the laboratory. Where do those scientists end up? What is it like for them to be part of a celebrated piece…

Planetary scientist and broadcaster Carl Sagan, who died in 1996, influenced some of NASA’s planetary missions.Credit: Science History Images/Alamy Early in 1993, a manuscript landed in the Nature offices announcing the results of an unusual — even audacious — experiment. The investigators, led by planetary scientist and broadcaster Carl Sagan, had searched for evidence of…

Hello Nature readers, would you like to get this Briefing in your inbox free every day? Sign up here. A new drug can alleviate loss of smell and taste caused by COVID-19.Credit: Angela Weiss/AFP via Getty COVID drug helps bring back sense of smell Clinical-trial data suggest that an antiviral pill called ensitrelvir is among…

A pair of cormorants thought to have died from H5N1 bird flu, found washed up on a beach in Chile earlier this year.Credit: Martin Bernetti/AFP via Getty Researchers studying the evolution of the bird flu virus over the past 18 years have shown how the strain currently circulating worldwide, an extremely deadly form of the…

Inspired by the classic lock-and-key model and advances in equivariant deep network design, we present a structure-based drug design model, SurfGen, which uses two types of equivariant graph neural networks to learn on protein surfaces and geometric structures to directly design small-molecule drugs. This is a preview of subscription content, access via your institution Access…