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The zettabyte era is in our DNA

Abstract

This Perspective surveys the critical computational challenges associated with in vitro DNA-based data storage. As digital data expand exponentially, traditional storage media are becoming less viable, making DNA a promising solution due to its density and durability. However, numerous obstacles remain, including error correction, data retrieval from large volumes of noisy reads, and scalability. The Perspective also highlights challenges for DNA-based data centers, such as fault tolerance, random access, and data removal, which must be addressed to make DNA-based storage practical.

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Fig. 1: Annual size of the global data sphere (ZB).
Fig. 2: A schematic representation of a DNA storage system.

References

  1. Coughlin, T. 175 zettabytes by 2025. Forbes https://www.forbes.com/sites/tomcoughlin/2018/11/27/175-zettabytes-by-2025/ (2018).

  2. Reinsel, D., Gantz, J. & Rydning, J. The Digitization of the World—from Edge to Core White Paper (International Data Corporation (IDC), 2018).

  3. Feynman, R. There’s plenty of room at the bottom. Eng. Sci. 23, 22–36 (1960).

    Google Scholar 

  4. Neiman, M. S. On the molecular memory systems and the directed mutations. Radiotekhnika 6, 1–8 (1965).

    Google Scholar 

  5. Markowitz, D. Biology is all you need. In The International Conference for High Performance Computing, Networking, Storage, and Analysis (November 2022).

  6. Preserving our Digital Legacy: an Introduction to DNA Data Storage White Paper (DNA Storage Alliance, 2021).

  7. Ceze, L., Nivala, J. & Strauss, K. Molecular digital data storage using DNA. Nat. Rev. Genet. 20, 456–466 (2019).

    Article 

    Google Scholar 

  8. Yang, S. et al. DNA as a universal chemical substrate for computing and data storage. Adv. Mater. 8, 179–194 (2024).

    Google Scholar 

  9. Shipman, S. L., Nivala, J., Macklis, J. D. & Church, G. M. CRISPR–Cas encoding of a digital movie into the genomes of a population of living bacteria. Nature 547, 345–349 (2017).

    Article 

    Google Scholar 

  10. Sun, F. et al. Mobile and self-sustained data storage in an extremophile genomic DNA. Adv. Sci. 10, 2206201 (2023).

    Article 

    Google Scholar 

  11. Chen, W. et al. An artificial chromosome for data storage. Natl Sci. Rev. 8, nwab028 (2021).

    Article 

    Google Scholar 

  12. Ham, T. S., Lee, S. K., Keasling, J. D. & Arkin, A. P. Design and construction of a double inversion recombination switch for heritable sequential genetic memory. PLoS ONE 3, e2815 (2008).

    Article 

    Google Scholar 

  13. Hou, Z. et al. Cell disk DNA storage system capable of random reading and rewriting. Adv. Sci. 11, 2305921 (2024).

    Article 

    Google Scholar 

  14. Wang, S., Mao, X., Wang, F., Zuo, X. & Fan, C. Data storage using DNA. Adv. Mater. 6, e2307499 (2024).

    Article 

    Google Scholar 

  15. LeProust, E. M. et al. Synthesis of high-quality libraries of long (150mer) oligonucleotides by a novel depurination controlled process. Nucleic Acids Res. 38, 2522–2540 (2010).

    Article 

    Google Scholar 

  16. Sabary, O. et al. SOLQC: Synthetic Oligo Library Quality Control tool. Bioinformatics 37, 720–722 (2021).

    Article 

    Google Scholar 

  17. Heckel, R., Mikutis, G. & Grass, R. N. A characterization of the DNA data storage channel. Sci. Rep. 9, 9663 (2019).

    Article 

    Google Scholar 

  18. Bar-Lev, D., Orr, I., Sabary, O., Etzion, T. & Yaakobi, E. Deep DNA storage: scalable and robust DNA storage via coding theory and deep learning. Preprint at https://doi.org/10.48550/arXiv.2109.00031 (2021).

  19. Organick, L. et al. Random access in large-scale DNA data storage. Nat. Biotechnol. 36, 242–248 (2018).

    Article 

    Google Scholar 

  20. Rashtchian, C. et al. Clustering billions of reads for DNA data storage. In Advances in Neural Information Processing Systems Vol. 30 (eds Guyon, I. et al.) (Curran, 2017).

  21. Sabary, O., Yucovich, A., Shapira, G. & Yaakobi, E. Reconstruction algorithms for DNA-storage systems. Sci. Rep. 14, 1951 (2024).

  22. Blawat, M. et al. Forward error correction for DNA data storage. Procedia Comput. Sci. 80, 1011–1022 (2016).

    Article 

    Google Scholar 

  23. Grass, R. N., Heckel, R., Puddu, M., Paunescu, D. & Stark, W. J. Robust chemical preservation of digital information on DNA in silica with error-correcting codes. Angew. Chem. Int. Ed. 54, 2552–2555 (2015).

    Article 

    Google Scholar 

  24. Qu, G., Yan, Z. & Wu, H. Clover: tree structure-based efficient DNA clustering for DNA-based data storage. Brief. Bioinform. 23, bbac336 (2022).

    Article 

    Google Scholar 

  25. Antkowiak, P. L. et al. Low cost DNA data storage using photolithographic synthesis and advanced information reconstruction and error correction. Nat. Commun. 11, 5345 (2020).

    Article 

    Google Scholar 

  26. Wang, Y., Zhao, Y., Bollas, A., Wang, Y. & Au, K. F. Nanopore sequencing technology, bioinformatics and applications. Nat. Biotechnol. 39, 1348–1365 (2021).

    Article 

    Google Scholar 

  27. Gopalan, P. S. et al. Trace reconstruction from noisy polynucleotide sequencer reads. US Patent 15/536,115 (2018).

  28. Srinivasavaradhan, S. R., Gopi, S., Pfister, H. & Yekhanin, S. Trellis BMA: coded trace reconstruction on IDS channels for DNA storage. In 2021 IEEE International Symposium on Information Theory (ISIT) 2453–2458 (IEEE, 2021).

  29. Pan, C. et al. Rewritable two-dimensional DNA-based data storage with machine learning reconstruction. Nat. Commun. 13, 2984 (2022).

    Article 

    Google Scholar 

  30. Erlich, Y. & Zielinski, D. DNA fountain enables a robust and efficient storage architecture. Science 355, 950–954 (2017).

    Article 

    Google Scholar 

  31. Ping, Z., Chen, S. & Zhou, G. Towards practical and robust DNA-based data archiving using the yin–yang codec system. Nat. Comput. Sci. 2, 234–242 (2022).

    Article 

    Google Scholar 

  32. Bar-Lev, D., Sabary, O., Gabrys, R. & Yaakobi, E. Cover your bases: how to minimize the sequencing coverage in DNA storage systems. In 2023 IEEE International Symposium on Information Theory (ISIT) 370–375 (IEEE, 2023).

  33. Chen, Y. J. et al. Quantifying molecular bias in DNA data storage. Nat. Commun. 11, 3264 (2020).

    Article 

    Google Scholar 

  34. Song, L. et al. Robust data storage in DNA by de Bruijn graph-based de novo strand assembly. Nat. Commun. 13, 5361 (2022).

    Article 

    Google Scholar 

  35. Mitzenmacher, M. A survey of results for deletion channels and related synchronization channels. Probab. Surv. 6, 1–33 (2009).

    Article 
    MathSciNet 

    Google Scholar 

  36. Press, W. H., Hawkins, J. A., Jones Jr, S. K., Schaub, J. M. & Finkelstein, I. J. HEDGES error-correcting code for DNA storage corrects indels and allows sequence constraints. Proc. Natl Acad. Sci. USA 117, 18489–18496 (2020).

    Article 

    Google Scholar 

  37. Maarouf, I. et al. Concatenated codes for multiple reads of a DNA sequence. IEEE Trans. Inf. Theory 69, 910–927 (2023).

    Article 
    MathSciNet 

    Google Scholar 

  38. Welzel, M. et al. DNA-Aeon provides flexible arithmetic coding for constraint adherence and error correction in DNA storage. Nat. Commun. 14, 628 (2023).

    Article 

    Google Scholar 

  39. Yan, Z., Liang, C. & Wu, H. A segmented-edit error-correcting code with re-synchronization function for DNA-based storage systems. IEEE Trans. Emerg. Top. Comput. 11, 605–618 (2022).

    Article 

    Google Scholar 

  40. Anavy, L., Vaknin, I., Atar, O., Amit, R. & Yakhini, Z. Data storage in DNA with fewer synthesis cycles using composite DNA letters. Nat. Biotechnol. 37, 1229–1236 (2019).

    Article 

    Google Scholar 

  41. Banal, J. L. et al. Random access DNA memory using Boolean search in an archival file storage system. Nat. Mater. 20, 1272–1280 (2021).

    Article 

    Google Scholar 

  42. Yazdi, S. M. H. T., Yuan, Y., Ma, J., Zhao, H. & Milenkovic, O. A rewritable, random-access DNA-based storage system. Nat. Sci. Rep. 5, 14138 (2015).

    Google Scholar 

  43. Plank, J. S. Erasure codes for storage systems: a brief primer. login 38, 44–50 (2013).

    Google Scholar 

  44. Bar-Lev, D., Etzion, T., Yaakobi, E. & Yakhini, Z. Representing information on DNA using patterns induced by enzymatic labeling. In 2024 IEEE International Symposium on Information Theory (ISIT) 1943–1948 (IEEE, 2024).

  45. Chakraborty, R. et al. Solid-state MoS2 nanopore membranes for discriminating among the lengths of RNA tails on a double-stranded DNA: a new simulation-based differentiating algorithm. ACS Appl. Nano Mater. 6, 4651–4660 (2023).

    Article 

    Google Scholar 

  46. Preuss, I., Rosenberg, M., Yakhini, Z. & Anavy, L. Efficient DNA-based data storage using shortmer combinatorial encoding. Sci. Rep. 14, 7731 (2024).

    Article 

    Google Scholar 

  47. Sadremomtaz, A. et al. Digital data storage on DNA tape using CRISPR base editors. Nat. Commun. 14, 6472 (2023).

    Article 

    Google Scholar 

  48. Tabatabaei, S. K. et al. DNA punch cards for storing data on native DNA sequences via enzymatic nicking. Nat. Commun. 11, 1742 (2020).

    Article 

    Google Scholar 

Download references

Acknowledgements

The research was funded by the European Union (ERC, DNAStorage, 865630). Views and opinions expressed are however those of the authors only and do not necessarily reflect those of the European Union or the European Research Council Executive Agency. Neither the European Union nor the granting authority can be held responsible for them.

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  1. The Henry and Marilyn Taub Faculty of Computer Science, Technion, Israel Institute of Technology, Haifa, Israel

    Daniella Bar-Lev, Omer Sabary & Eitan Yaakobi

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  1. Daniella Bar-Lev
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Bar-Lev, D., Sabary, O. & Yaakobi, E. The zettabyte era is in our DNA.
Nat Comput Sci (2024). https://doi.org/10.1038/s43588-024-00717-1

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  • Received: 06 June 2023

  • Accepted: 03 October 2024

  • Published: 08 November 2024

  • DOI: https://doi.org/10.1038/s43588-024-00717-1

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