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A geometry-based approach to make viable-cell counting easy and cheap

Counting the number of viable cells in a culture remains a critical measurement in microbiology, but traditional dilution assays are time- and reagent-consuming. We developed the geometric viability assay that overcomes these limitations by leveraging microbial colony distribution in a cone — a pipette tip — to calculate viability across six orders of magnitude.

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Fig. 1: The GVA.

References

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This is a summary of: Meyer, C. T. et al. A high-throughput and low-waste viability assay for microbes. Nat. Microbiol. https://doi.org/10.1038/s41564-023-01513-9 (2023).

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A geometry-based approach to make viable-cell counting easy and cheap.
Nat Microbiol (2023). https://doi.org/10.1038/s41564-023-01522-8

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  • Published: 22 November 2023

  • DOI: https://doi.org/10.1038/s41564-023-01522-8

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