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On the 50th anniversary of the Endangered Species Act, a rightwing threat looms
Imagine a cosmic rock billions of years old yet vibrant with water, light and life. Not too close to the sun and not too far away. Tilted on its axis and turning daily to render seasons, sunrises and sunsets. A place so bountiful and varied that it has nourished and inspired humanity through our entire…
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Trump’s Polarization of Science Is Bad for Everyone
The president of the United States cannot control the trajectory of a hurricane, but he can—we learned in 2019—force the National Oceanic and Atmospheric Administration to endorse a trajectory that he invented. Thus went Sharpiegate, the brief episode that began when Donald Trump tweeted a warning about Hurricane Dorian’s danger to several states. It was…
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Science ‘indisputable, unassailable’ world needs to be non-emission to limit warming: UN Environment Program chief
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Cop28 live: energy in focus after scientists reject president’s fossil fuel comments
Mary Robinson has made her first comment since the row over the Cop28 president’s controversial and ill-tempered response to her questions on the need for a fossil fuel phase out, revealed by the Guardian. Robinson, chair of the Elders and a former president of the Republic of Ireland, has taken a diplomatic approach, as perhaps…
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Museum of Life and Science Announces Arrival of Male Red Wolf Adeyha
The Museum of Life and Science in Durham, N.C., recently welcomed a new addition to its red wolf family. Adeyha (M2080), a male red wolf from the Niabi Zoo in Coal Valley, Ill., has joined the Museum in exchange for Niko (M2164). Meanwhile, the female red wolf, Oak (F2304), remains with the Museum. The Museum of…
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Broaden scope of review boards to boost public trust
Flawed or faked research studies are fuelling a public mistrust in biomedical science (see, for example, Nature 619, 454–458; 2023). Public trust in research is essential for scientific progress because it correlates with funding and policy decisions, research participation and an openness to evolving evidence. I propose that independent ethics review boards could help to…
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Dysregulated wound healing in the pathogenesis of urogynecologic mesh complications
Abstract To test the hypothesis that dysregulated wound healing is associated with Urogynecologic mesh complications, we collected vaginal cell secretions using vaginal swabs after polypropylene mesh implantation in patients with (N = 39) and without (N = 40) complication. A customized multiplex immunoassay measured markers of inflammation (MCP-1, IGFBP-1, IL-2, IL-10, IL-17, PDGF-BB, bFGF, IL-1b, IL-6, IL-12p70, TNF-α), neuroinflammation…
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Scientists skip COP28 to demand climate action at home
Members of two activist groups, Scientist Rebellion and Just Stop Coal, blocked a train track on 4 December to demand that Denmark phase out fossil fuels such as coal.Credit: Scientist Rebellion NL & kappen met kolen NL Some scientists-turned-activists have changed tactics during this year’s United Nations climate summit. Rather than staging demonstrations in Dubai,…
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SAM, SAH and C. elegans longevity: insights from a partial AHCY deficiency model
Abstract Supplementation with S-adenosylhomocysteine (SAH) extends the lifespan of model organisms. To explore the impact of SAH on aging, we generated a Caenorhabditis elegans model by introducing the S-adenosylhomocysteine hydrolase (AHCY-1) variant Y145C, corresponding to the human AHCY Y143C pathogenic mutation. This mutation is anticipated to impair SAH hydrolysis, resulting in its increased levels. Our…
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Vitamin B12 boosts cellular reprogramming
“There is currently a lot of interest in cellular reprogramming, yet we still know very little about the mechanisms of in vivo reprogramming, its metabolic requirements and how to control it. We thought that by studying the microbiota — a community of microorganisms that is in metabolic equilibrium with its host — during in vivo…