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Nature-based climate solutions: align policy with science
The US Congress is crafting legislation for the Farm Bill, a multi-year law bolstered by Inflation Reduction Act (IRA) provisions. The IRA allocated US$15 billion for oversubscribed conservation initiatives, including $300 million for research needed for effective nature-based climate solutions. This crucial research funding is now under threat of reallocation (see go.nature.com/3rjx7uy), which would severely…
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Most scientists don’t enjoy writing grants. Here’s how to change that
Working in a group can give a sense of community to the process of writing grant applications.Credit: Getty What words come to mind when you think of preparing research proposals? The odds are that ‘excited’ and ‘happy’ are not among them. We regularly provide grant-writing training to academics of all career stages at Stanford University…
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ABP1’s new partners
The research history of the auxin-binding protein ABP1 is convoluted and serves as an excellent example of nonlinear scientific progress. It was a promising extracellular auxin receptor in the long ‘Antique period’, roughly between the 1970s and 1990s. The ‘Dark Ages’ started in 2005 after interest shifted owing to the discovery of TIR1 as a…
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Can a functional ecological model reliably reveal the nature of early plant management in southwest Asia?
arising from A. Weide et al. Nature Plants https://doi.org/10.1038/s41477-022-01161-7 (2022) This is a preview of subscription content, access via your institution Access options Access through your institution Change institution Buy or subscribe /* style specs start */ style{display:none!important}.LiveAreaSection-193358632 *{align-content:stretch;align-items:stretch;align-self:auto;animation-delay:0s;animation-direction:normal;animation-duration:0s;animation-fill-mode:none;animation-iteration-count:1;animation-name:none;animation-play-state:running;animation-timing-function:ease;azimuth:center;backface-visibility:visible;background-attachment:scroll;background-blend-mode:normal;background-clip:borderBox;background-color:transparent;background-image:none;background-origin:paddingBox;background-position:0 0;background-repeat:repeat;background-size:auto 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Broaden scope of review boards to boost public trust
Flawed or faked research studies are fuelling a public mistrust in biomedical science (see, for example, Nature 619, 454–458; 2023). Public trust in research is essential for scientific progress because it correlates with funding and policy decisions, research participation and an openness to evolving evidence. I propose that independent ethics review boards could help to…
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Dysregulated wound healing in the pathogenesis of urogynecologic mesh complications
Abstract To test the hypothesis that dysregulated wound healing is associated with Urogynecologic mesh complications, we collected vaginal cell secretions using vaginal swabs after polypropylene mesh implantation in patients with (N = 39) and without (N = 40) complication. A customized multiplex immunoassay measured markers of inflammation (MCP-1, IGFBP-1, IL-2, IL-10, IL-17, PDGF-BB, bFGF, IL-1b, IL-6, IL-12p70, TNF-α), neuroinflammation…
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Scientists skip COP28 to demand climate action at home
Members of two activist groups, Scientist Rebellion and Just Stop Coal, blocked a train track on 4 December to demand that Denmark phase out fossil fuels such as coal.Credit: Scientist Rebellion NL & kappen met kolen NL Some scientists-turned-activists have changed tactics during this year’s United Nations climate summit. Rather than staging demonstrations in Dubai,…
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SAM, SAH and C. elegans longevity: insights from a partial AHCY deficiency model
Abstract Supplementation with S-adenosylhomocysteine (SAH) extends the lifespan of model organisms. To explore the impact of SAH on aging, we generated a Caenorhabditis elegans model by introducing the S-adenosylhomocysteine hydrolase (AHCY-1) variant Y145C, corresponding to the human AHCY Y143C pathogenic mutation. This mutation is anticipated to impair SAH hydrolysis, resulting in its increased levels. Our…
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Vitamin B12 boosts cellular reprogramming
“There is currently a lot of interest in cellular reprogramming, yet we still know very little about the mechanisms of in vivo reprogramming, its metabolic requirements and how to control it. We thought that by studying the microbiota — a community of microorganisms that is in metabolic equilibrium with its host — during in vivo…
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Climate researchers need support to become scientist-communicators
In the early morning of 16 August 2020, the first lightning strikes arrived, and with them the e-mails and phone calls. Over the next 3 days, more than 10,000 lightning strikes from ‘dry’ thunderstorms ignited hundreds of wildfires in California. In the days and weeks that followed, California was besieged by an unprecedented sequence of…