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Scientists skip COP28 to demand climate action at home
Members of two activist groups, Scientist Rebellion and Just Stop Coal, blocked a train track on 4 December to demand that Denmark phase out fossil fuels such as coal.Credit: Scientist Rebellion NL & kappen met kolen NL Some scientists-turned-activists have changed tactics during this year’s United Nations climate summit. Rather than staging demonstrations in Dubai,…
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SAM, SAH and C. elegans longevity: insights from a partial AHCY deficiency model
Abstract Supplementation with S-adenosylhomocysteine (SAH) extends the lifespan of model organisms. To explore the impact of SAH on aging, we generated a Caenorhabditis elegans model by introducing the S-adenosylhomocysteine hydrolase (AHCY-1) variant Y145C, corresponding to the human AHCY Y143C pathogenic mutation. This mutation is anticipated to impair SAH hydrolysis, resulting in its increased levels. Our…
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Vitamin B12 boosts cellular reprogramming
“There is currently a lot of interest in cellular reprogramming, yet we still know very little about the mechanisms of in vivo reprogramming, its metabolic requirements and how to control it. We thought that by studying the microbiota — a community of microorganisms that is in metabolic equilibrium with its host — during in vivo…
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Climate researchers need support to become scientist-communicators
In the early morning of 16 August 2020, the first lightning strikes arrived, and with them the e-mails and phone calls. Over the next 3 days, more than 10,000 lightning strikes from ‘dry’ thunderstorms ignited hundreds of wildfires in California. In the days and weeks that followed, California was besieged by an unprecedented sequence of…
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NONAN GaitPrint: An IMU gait database of healthy young adults
Abstract An ongoing thrust of research focused on human gait pertains to identifying individuals based on gait patterns. However, no existing gait database supports modeling efforts to assess gait patterns unique to individuals. Hence, we introduce the Nonlinear Analysis Core (NONAN) GaitPrint database containing whole body kinematics and foot placement during self-paced overground walking on…
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Guest edited collection: fungal evolution and diversity
There are 5 million fungal species. However, the discovery and classification of fungi are in high flux. Modern concepts indicate that the three kingdoms of “fungi” are Chromista, Fungi and Protozoa. Strong support for the wrong phylogeny can occur without correct analytical methods. In the current Collection we envisaged fungi representing extremely diverse and ancient…
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Is AI leading to a reproducibility crisis in science?
During the COVID-19 pandemic in late 2020, testing kits for the viral infection were scant in some countries. So the idea of diagnosing infection with a medical technique that was already widespread — chest X-rays — sounded appealing. Although the human eye can’t reliably discern differences between infected and non-infected individuals, a team in India…
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Revisiting the use of structural similarity index in Hi-C
arising from S. Galan et al. 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Integral Ad Science Announces Launch of Secondary Offering of Common Stock by Selling Stockholders
NEW YORK, Dec. 4, 2023 /PRNewswire/ — Integral Ad Science Holding Corp. (Nasdaq: IAS), a leading global media measurement and optimization platform, today announced the commencement of a public offering of its common stock by investment funds affiliated with Vista Equity Partners (the “Selling Stockholders“). The Selling Stockholders are offering 11,000,000 shares of IAS’s common…
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Modern US earthquakes could be century-old aftershocks, study says
Sign up for CNN’s Wonder Theory science newsletter. Explore the universe with news on fascinating discoveries, scientific advancements and more. CNN — After large earthquakes, there is an expectation that aftershocks could occur in the hours and days that follow, but aftershocks from some of the strongest earthquakes in recorded United States history may still be…