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SAM, SAH and C. elegans longevity: insights from a partial AHCY deficiency model
Abstract Supplementation with S-adenosylhomocysteine (SAH) extends the lifespan of model organisms. To explore the impact of SAH on aging, we generated a Caenorhabditis elegans model by introducing the S-adenosylhomocysteine hydrolase (AHCY-1) variant Y145C, corresponding to the human AHCY Y143C pathogenic mutation. This mutation is anticipated to impair SAH hydrolysis, resulting in its increased levels. Our…
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Vitamin B12 boosts cellular reprogramming
“There is currently a lot of interest in cellular reprogramming, yet we still know very little about the mechanisms of in vivo reprogramming, its metabolic requirements and how to control it. We thought that by studying the microbiota — a community of microorganisms that is in metabolic equilibrium with its host — during in vivo…
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Climate researchers need support to become scientist-communicators
In the early morning of 16 August 2020, the first lightning strikes arrived, and with them the e-mails and phone calls. Over the next 3 days, more than 10,000 lightning strikes from ‘dry’ thunderstorms ignited hundreds of wildfires in California. In the days and weeks that followed, California was besieged by an unprecedented sequence of…
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NONAN GaitPrint: An IMU gait database of healthy young adults
Abstract An ongoing thrust of research focused on human gait pertains to identifying individuals based on gait patterns. However, no existing gait database supports modeling efforts to assess gait patterns unique to individuals. Hence, we introduce the Nonlinear Analysis Core (NONAN) GaitPrint database containing whole body kinematics and foot placement during self-paced overground walking on…
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Guest edited collection: fungal evolution and diversity
There are 5 million fungal species. However, the discovery and classification of fungi are in high flux. Modern concepts indicate that the three kingdoms of “fungi” are Chromista, Fungi and Protozoa. Strong support for the wrong phylogeny can occur without correct analytical methods. In the current Collection we envisaged fungi representing extremely diverse and ancient…
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Integral Ad Science Announces Launch of Secondary Offering of Common Stock by Selling Stockholders
NEW YORK, Dec. 4, 2023 /PRNewswire/ — Integral Ad Science Holding Corp. (Nasdaq: IAS), a leading global media measurement and optimization platform, today announced the commencement of a public offering of its common stock by investment funds affiliated with Vista Equity Partners (the “Selling Stockholders“). The Selling Stockholders are offering 11,000,000 shares of IAS’s common…
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Modern US earthquakes could be century-old aftershocks, study says
Sign up for CNN’s Wonder Theory science newsletter. Explore the universe with news on fascinating discoveries, scientific advancements and more. CNN — After large earthquakes, there is an expectation that aftershocks could occur in the hours and days that follow, but aftershocks from some of the strongest earthquakes in recorded United States history may still be…
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Improved Tracking and Incentives Needed to Address Near-term Climate Change
An increasing number of companies have aggressive, immediate goals to reduce their greenhouse gas emissions with the goal of tackling climate change over the long run, as well as addressing the impacts already being experienced today. However, immediate cuts to emissions of long-lived climate pollutants (LLCPs) like carbon dioxide (CO2), will not mitigate the effects…
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St. Thomas Launches AI Master of Science Degree – Newsroom | University of St. Thomas
The latest master’s degree program offered by Minnesota’s largest private university addresses a growing need for organizations seeking skilled professionals who can harness the power of artificial intelligence to enhance efficiency, make data-driven decisions and innovate. The University of St. Thomas’ Master of Science in Artificial Intelligence, which was developed in consultation with Twin Cities…
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The Nature Conservancy completes first timber harvest at Slate River Forest Reserve
BARAGA COUNTY, Mich. — The Nature Conservancy in Michigan (TNC) recently completed the first timber harvest at its Slate River Forest Reserve. This is the first timber harvest at the reserve since TNC purchased the more than 10,000 acres in 2021. The sale was planned, prepared and marketed by TNC and Huber Resources Corp. foresters.…