Internal clocks Animal studies have shown that the ageing process varies not only between individuals but also between organs within an individual. In this week’s issue, Tony Wyss-Coray and his colleagues reveal that this ageing difference holds true for humans, too. The researchers assessed levels of human blood plasma proteins originating from 11 organs to…

The US Congress is crafting legislation for the Farm Bill, a multi-year law bolstered by Inflation Reduction Act (IRA) provisions. The IRA allocated US$15 billion for oversubscribed conservation initiatives, including $300 million for research needed for effective nature-based climate solutions. This crucial research funding is now under threat of reallocation (see go.nature.com/3rjx7uy), which would severely…

The research history of the auxin-binding protein ABP1 is convoluted and serves as an excellent example of nonlinear scientific progress. It was a promising extracellular auxin receptor in the long ‘Antique period’, roughly between the 1970s and 1990s. The ‘Dark Ages’ started in 2005 after interest shifted owing to the discovery of TIR1 as a…

arising from A. Weide et al. 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“There is currently a lot of interest in cellular reprogramming, yet we still know very little about the mechanisms of in vivo reprogramming, its metabolic requirements and how to control it. We thought that by studying the microbiota — a community of microorganisms that is in metabolic equilibrium with its host — during in vivo…