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What we actually know about aliens, according to science
GREEN BANK, W.Va. — It came from space, hurtling at tremendous speed: a mystery object, reddish, rocky, shaped like a cigar. Its velocity was so extreme it had to have come from somewhere far away, in the interstellar realm. The astronomers in Hawaii who spotted it in 2017 named it ‘Oumuamua, Hawaiian for “a messenger…
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Fred Allendorf: Science and Nature: Nobel Prize awarded for the COVID-19 vaccine
FRED ALLENDORF The 2023 Nobel Prize in Medicine was awarded recently to Katalin Karikó and Drew Weissman for their discoveries that enabled the development of mRNA (messenger RNA) vaccines for immunization against the coronavirus that causes COVID-19. According to the committee, “The vaccines have saved millions of lives and prevented severe disease in many more,…
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Tallman: World conflicts ‘last gasp’ of old regime, as humans evolve toward unity, harmony with nature
Breadcrumb Trail Links Columnists The end times depicted in Revelation, the last book of the Christian scriptures, are a cataclysm of vast destruction and glory. Author of the article: Bruce Tallman • Special to The London Free Press Published Nov 25, 2023 • Last updated 3 hours ago • 3 minute read Join the conversation The…
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Temperature variation in caves and its significance for subterranean ecosystems
Abstract Climate change affects all ecosystems, but subterranean ecosystems are repeatedly neglected from political and public agendas. Cave habitats are home to unknown and endangered species, with low trait variability and intrinsic vulnerability to recover from human-induced disturbances. We studied the annual variability and cyclicity of temperatures in caves vis-à-vis surface in different climatic areas.…
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Retroperitoneal totally endoscopic prosthetic repair of lumbar hernia
Abstract Lumbar hernia is a rare lateral abdominal wall hernia. Various surgical repair strategies have been recorded, but there is currently no unified standard. A Chinese surgeon recently revealed a novel technique for treating primary lumbar hernia called retroperitoneal totally endoscopic prosthetic repair (R-TEP). We have made a further exploration of this method and successfully…
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A positive feedback loop regulation between NOTCH1 and USP11 in T-cell leukemia
To the Editor: NOTCH1 is a transmembrane receptor in a highly conserved signaling pathway that controls cell fate decisions in various organisms and tissues. In contrast, its dysregulation is associated with developmental disorders transformation [1]. NOTCH1 is composed of extracellular and intracellular domains. Ligand binding of NOTCH1 extracellular domain leads to two consecutive cleavage steps…
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Muscle activity variability patterns and stride to stride fluctuations of older adults are positively correlated during walking
Abstract It has been found that fractal-like patterns are present in the temporal structure of the variability of healthy biological rhythms, while pathology and disease lead to their deterioration. Interestingly, it has recently been suggested that these patterns in biological rhythms are related with each other, reflecting overall health or lack of it, due to…
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Implementing quality management systems to close the AI translation gap and facilitate safe, ethical, and effective health AI solutions
The integration of Quality Management System (QMS) principles into the life cycle of development, deployment, and utilization of machine learning (ML) and artificial intelligence (AI) technologies within healthcare settings holds the potential to close the AI translation gap by establishing a robust framework that accelerates the safe, ethical, and effective delivery of AI/ML in day-to-day…
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Essential oil components of turmeric inhibit hepatic lipidification and liver fibrosis in a diet-induced NASH model rats
Abstract In this study, the fraction extracted from turmeric powder with 50% ethanol and fractionated with n-hexane were administered to diet-induced NASH model rats. NASH model was prepared with SD rats by feeding an originally designed choline-deficient, high-fat, high-fructose (HFF-CD) diet for 10 weeks. To the HFF-CD diet, hexane fraction and 50% ethanol fraction after hexane…
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Structured dataset of human-machine interactions enabling adaptive user interfaces
Abstract This article introduces a dataset of human-machine interactions collected in a controlled and structured manner. The aim of this dataset is to provide insights into user behavior and support the development of adaptive Human-Machine Interfaces (HMIs). The dataset was generated using a custom-built application that leverages formally defined User Interfaces (UIs). The resulting interactions…