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Audio long read: Apple revival — how science is bringing historic varieties back to life
Download the 24 November long read podcast Researchers have been resurrecting apple trees to revive forgotten varieties of the fruit. They hope that sequencing these apples’ genomes could uncover mutations that influence flavour, colour, crispness and other characteristics. This knowledge could help unlock the next blockbuster fruit, and develop trees that are more resistant to…
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Observations of amyloid breakdown by proteases over time using scanning acoustic microscopy
Abstract Amyloid consists of insoluble beta-fibrillar proteins with stable structures. The Congo red staining method for histologically detecting amyloid is unsuitable for quantitatively assessing amyloid fibers. Scanning acoustic microscopy (SAM) detects the attenuation of sound (AOS) through sections. This study aimed to clarify whether AOS values reflected the amount of amyloid fibril degradation in tissues.…
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GLP-1 receptor agonists are promising but unproven treatments for alcohol and substance use disorders
Preclinical and initial human studies suggest that glucagon-like peptide-1 receptor agonists may be promising treatments for alcohol use disorder, but existing approved treatments should be used until safety and efficacy is demonstrated in clinical trials. This is a preview of subscription content, access via your institution Access options Access through your institution Change institution Buy…
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How ChatGPT and sounds from space brought a “luminous jelly” to life
Your browser does not support the audio element. Download MP3 See transcript GUI/GOOEY is an international online exhibition that explores digital and technological representations of the biological world. In the fourth episode of this six-part Working Scientist podcast series about art and science, Julie Gould talks to some of the artists and scientist whose collaborations…
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Adaptation constraints in scenarios of socio-economic development
Abstract Climate change adaptation is paramount, but increasing evidence suggests that adaptation action is subject to a range of constraints. For a realistic assessment of future adaptation prospects, it is crucial to understand the timescales needed to overcome these constraints. Here, we combine data on documented adaptation from the Global Adaptation Mapping Initiative with national…
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Hyperspectral screen-image-synthesis meter with scattering-noise suppression
Abstract The screen image synthesis (SIS) meter was originally proposed as a high-speed measurement tool, which fused the measured data from multiple sample-rotational angles to produce a whole-field measurement result. However, it suffered from stray light noise and lacked the capability of spectrum measurement. In this study, we propose an SIS system embedded with a…
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Quality inspection of specific electronic boards by deep neural networks
Abstract Reliability and lifetime of specific electronics boards depends on the quality of manufacturing process. Especially soldering splashes in some areas of PCB (printed circuit board) can cause change of selected electrical parameters. Nowadays, the manual inspection is massively replaced by specialized visual systems checking the presence of different defects. The research carried out in…
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Gut microbial signatures are associated with Lynch syndrome (LS) and cancer history in Druze communities in Israel
Abstract Lynch syndrome (LS) is a hereditary cancer syndrome caused by autosomal dominant mutations, with high probability of early onset for several cancers, mainly colorectal cancer (CRC). The gut microbiome was shown to be influenced by host genetics and to be altered during cancer development. Therefore, we aimed to determine alterations in gut microbiome compositions…
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Disaster risk communication requires dissemination, dialogue and participation
Disaster risk communication traditionally focuses on authorities conveying hazard and risk information to at-risk populations, with little consideration of local community knowledge. To enable risk reduction and resilience, disaster management must forge partnerships with local communities and empower citizen-led initiatives. Disasters triggered by natural and human-induced shocks are hugely complex societal incidents, often striking with…
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G7 to Share Information on Invasive Alien Species; Members Agree to Create Database, Strengthen Research
Courtesy of Environment MinistryFire ants, an alien species that has made particular inroads into Japan The Yomiuri Shimbun 7:00 JST, November 24, 2023 The Group of Seven has finalized action goals for invasive alien species that are threatening ecosystems in various regions, including the sharing of information on how such species get in and countermeasures at…