Labs range in size, and no one size is likely to fit all. Here some researchers share their lab size experiences and preferences. With lab size, says Lars Juhl Jensen of the University of Copenhagen, who works in proteomics, network biology and text mining, “it’s always a tradeoff.” Getting things done takes a critical mass…

Abstract In cis and trans geometrical configurations of the polyacetylene molecule, one-dimensional chain is constructed by attaching a number of identical –HC=CH– units one-by-one. We attach as many units as required to obtain the chain of the desired length. In case of a very long polyacetylene chain, which is practically considered infinite in length, a…

Abstract Botulinum neurotoxin (BoNT) shows high lethality and toxicity, marking it as an important biological threat. The only effective post-exposure therapy is botulinum antitoxin; however, such products have great potential for improvement. To prevent or treat BoNT, monoclonal antibodies (mAbs) are promising agents. Herein, we aimed to construct a bispecific antibody (termed LUZ-A1-A3) based on…

Abstract Within ice core science, woman-led studies contain 20% more women co-authors than man-led studies, and exceed the estimated proportion of women within the community by nearly 10%. We conclude that collaboration with other women is a key factor in closing gender gaps in science. This is a preview of subscription content, access via your…

There is something strange about the chemical bond. It is very difficult to define in a more sophisticated way than as being the ‘glue’ that ‘binds’ atoms. And yet the bond is one of the most essential concepts in chemistry; without it one cannot describe how molecules are structured, nor explain how a chemical reaction…

Cancer-cell nuclei (green boxes) picked out by software using deep learning.Credit: A. Diosdi – imaging; T. Toth & F. Kovacs – analysis; A. Kriston – visualization/BIOMAG/HUN-REN/SZBK Any biology student can pick a neuron out of a photograph. Training a computer to do the same thing is much harder. Jan Funke, a computational biologist at the…

In this issue, Harrold et al. [1] report outcomes at 52-weeks of their randomised controlled trial (RCT), called SWITCH, which compared consumption of beverages sweetened with non-nutritive sweeteners (NNS), with consumption of water. The authors deserve to be congratulated on performing a well-powered, long-term RCT with significant relevance to public health – in part they…

Abstract During the first two decades of the twenty-first century, the USA experienced a crisis of increasing psychological distress that was associated with rising morbidity and mortality, especially among young people. The increasing distress probably arose from changing economic, social, technological and political conditions that, unabated, may continue to progress in coming years. The increasing…

Abstract During the continuous charge and discharge process in lithium-sulfur batteries, one of the next-generation batteries, polysulfides are generated in the battery’s electrolyte, and impact its performance in terms of power and capacity by involving the process. The amount of polysulfides in the electrolyte could be estimated by the change of the Gibbs free energy…