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Drug discovery with limited resources
Recent estimates have indicated that the median cost of researching and developing a drug is over US$1 billion per drug, with research and development taking an average of ten years. Thus, using machine learning (ML) to accelerate research timelines and reduce development costs is an appealing avenue, particularly for drug discovery centers in lower-to-middle-income countries…
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ChatGPT use shows that the grant-application system is broken
Juan Manuel Parrilla questions how much value there is in aspects of the grant-application process.Credit: Juan Manuel Parrilla Gutierrez I’ve always hated writing grants. Like most scientists, I love having scientific ideas, and I love drawing diagrams and writing up my ideas. But grant applications require an enormous amount of work beyond conveying an idea…
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ChatGPT use shows that the grant-application system is broken
Juan Manuel Parrilla questions how much value there is in aspects of the grant-application process.Credit: Juan Manuel Parrilla Gutierrez I’ve always hated writing grants. Like most scientists, I love having scientific ideas, and I love drawing diagrams and writing up my ideas. But grant applications require an enormous amount of work beyond conveying an idea…
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Reproducibility trial: 246 biologists get different results from same data sets
Scientists who ran separate analyses on a single data set about the effect of grass cover on Eucalyptus seedlings arrived at vastly different answers.Credit: Laurence Dutton/Getty In a massive exercise to examine reproducibility, more than 200 biologists analysed the same sets of ecological data — and got widely divergent results. The first sweeping study1 of…
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Reproducibility trial: 246 biologists get different results from same data sets
Scientists who ran separate analyses on a single data set about the effect of grass cover on Eucalyptus seedlings arrived at vastly different answers.Credit: Laurence Dutton/Getty In a massive exercise to examine reproducibility, more than 200 biologists analysed the same sets of ecological data — and got widely divergent results. The first sweeping study1 of…
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This is the largest map of the human brain ever made
Insights into thousands of types of brain cell could improve understanding of diseases and cognition.Credit: Dennis Kunkel Microscopy/Science Photo Library Researchers have created the largest atlas of human brain cells so far, revealing more than 3,000 cell types — many of which are new to science. The work, published in a package of 21 papers…
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This is the largest map of the human brain ever made
Insights into thousands of types of brain cell could improve understanding of diseases and cognition.Credit: Dennis Kunkel Microscopy/Science Photo Library Researchers have created the largest atlas of human brain cells so far, revealing more than 3,000 cell types — many of which are new to science. The work, published in a package of 21 papers…
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Achieving UN climate goals needs purposeful, persistent action from science
A Canadair firefighting plane sprays water during a fire in Dervenochoria, northwest of Athens, in July.Credit: Spyros Bakalis/AFP via Getty When it comes to the alarmingly slow progress that the world is making towards the Sustainable Development Goals (SDGs) — United Nations targets set in 2015 to end poverty, achieve equality and protect the environment…
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Achieving UN climate goals needs purposeful, persistent action from science
A Canadair firefighting plane sprays water during a fire in Dervenochoria, northwest of Athens, in July.Credit: Spyros Bakalis/AFP via Getty When it comes to the alarmingly slow progress that the world is making towards the Sustainable Development Goals (SDGs) — United Nations targets set in 2015 to end poverty, achieve equality and protect the environment…
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AI and science: what 1,600 researchers think
Illustration by Acapulco Studio Artificial-intelligence (AI) tools are becoming increasingly common in science, and many scientists anticipate that they will soon be central to the practice of research, suggests a Nature survey of more than 1,600 researchers around the world. Science and the new age of AI: a Nature special When respondents were asked how…