Abstract Ophthalmic preparations that contain ketorolac tromethamine (KET) and olopatadine HCl (OLO) are used to relieve seasonal allergies and allergic conjunctivitis. Simultaneous quantification of KET and OLO was held by validated and simple spectrophotometric methods. KET was determined directly from the fundamental UV absorption spectra (at 323 nm), while OLO was determined after performing either dual…

Abstract Pesticides are widely used in global agriculture to achieve high productivity levels. Among them, fungicides are specifically designed to inhibit fungal growth in crops and seeds. However, their application often results in environmental contamination, as these chemicals can persistently be detected in surface waters. This poses a potential threat to non-target organisms, including humans,…

Abstract Mosquitoes interact with various organisms in the environment, and female mosquitoes in particular serve as vectors that directly transmit a number of microorganisms to humans and animals by blood-sucking. Comprehensive analysis of mosquito-borne viruses has led to the understanding of the existence of diverse viral species and to the identification of zoonotic arboviruses responsible…

Jordan Perchik started his radiology residency at the University of Alabama at Birmingham near the peak of what he calls the field’s “AI scare”. It was 2018, just two years after computer scientist Geoffrey Hinton had proclaimed that people should stop training to be radiologists because machine-learning tools would soon displace them. Hinton, sometimes referred…

Abstract Brain aging causes a progressive decline in functional capacity and is a strong risk factor for dementias such as Alzheimer’s disease. To characterize age-related proteomic changes in the brain, we used quantitative proteomics to examine brain tissues, cortex and hippocampus, of mice at three age points (3, 15, and 24 months old), and quantified more…

Abstract We present a combined experimental and theoretical study of the Se-treated GaAs(001)-((2times 1)) surface. The ((2times 1)) structure with the two-fold coordinated Se atom at the outermost layer and the three-fold coordinated Se atom at the third layer was found to be energetically stable and agrees well with the experimental data from scanning tunneling…

Abstract This study aimed at predicting the filtration surgery (FS) outcome using a machine learning (ML) approach. 102 glaucomatous patients undergoing FS were enrolled and underwent ocular surface clinical tests (OSCTs), determination of surgical site-related biometric parameters (SSPs) and conjunctival vascularization. Break-up-time, Schirmer test I, corneal fluorescein staining, Meibomian gland expressibility; conjunctival hyperemia, upper bulbar…

Abstract Activity scheduling represents a key process in daily life, involving the evaluation of the costs and benefits of the resources to be invested, but also a preference for when to engage in pleasant or unpleasant activities. Aging affects the evaluation processes and individual preferences due to changes in cognitive functioning and life perspectives. The…

Illustration by Fabrizio Lenci When Manuel Chevalier met Mine Altinli in Montpellier, France, both were in their late twenties. Chevalier was wrapping up his doctoral thesis on southern Africa’s past climates, whereas Altinli had just embarked on a PhD on how infections develop. Both were excited about a career in academia. “I expected to be…

To the Editor: In his recent essay, Johann Neem asks “Where Does the Thinking Happen?” “The thinking”? “Thinking happen”? It’s 2023.…  Neem writes as if the last 75 to 100 years of intellectual and higher educational history did not occur. His comments are rooted in the periodic rediscovery or echoing of novelist and occasional scientist…