Senescent cells (SnCs) accumulate in multiple tissue types with the process of individual aging, hindering tissue renewal and driving multiple aging-related disorders. Aside from senescence-associated secretory phenotype (SASP) neutralization and senolytics, there is an emerging senolysis strategy to eliminate SnCs by mobilizing the immunosurveillance function of cytotoxic T lymphocytes (CTLs). Emerging interest in senolysis during…

Abstract A method for a permanent surface modification of polydimethylsiloxane (PDMS) is presented. A case study on the attachment of PDMS and the lithium niobate (LiNbO3) wafer for acoustofluidics applications is presented as well. The method includes a protocol for chemically treating the surface of PDMS to strengthen its bond with the LiNbO3 surface. The…

Abstract Ophthalmic preparations that contain ketorolac tromethamine (KET) and olopatadine HCl (OLO) are used to relieve seasonal allergies and allergic conjunctivitis. Simultaneous quantification of KET and OLO was held by validated and simple spectrophotometric methods. KET was determined directly from the fundamental UV absorption spectra (at 323 nm), while OLO was determined after performing either dual…

Medical Detectives takes students on deep dive into science Published 6:00 pm Monday, October 23, 2023 1 of 5 IJ Holton Intermediate School students work to get to the bottom of an epidemic as part of Medical Detectives Mondat at The Hormel Institute. Eric Johnson/[email protected] IJ Holton Intermediate School students work to get to the…

At a crucial time for the conservation of the ocean and coastlines, Christopher McGuire, Ocean Program Director for The Nature Conservancy in Massachusetts, will lead the Advisory Council for Stellwagen Bank National Marine Sanctuary. Stellwagen Bank National Marine Sanctuary is a part of the ocean east of Boston, Massachusetts between Cape Ann and Cape Cod.…

Summers in New York City are like none other. In my memories of growing up in Queens in the 2000s, I can still hear the laughter of children echoing through the streets, reminding me that this bustling metropolis was our playground, our sanctuary for adventure. The streets were filled with people—families strolling hand-in-hand and friends…

By Carlyn Kranking Assistant Editor, Science and Innovation As darkness descends across the eastern coast of Australia, thousands of gray-headed flying foxes take to the skies. Armed with a keen sense of smell and sharp night vision, they roam to find food after resting all day. Some might travel as far as 30 miles in…

The European Commission published its European Wind Power Action Plan, presenting policy measures to support the European wind sector to reach the EU’s climate and decarbonisation targets. The Action Plan was announced by President von der Leyen last month during the State of the Union address and contains several new initiatives as well as actions…

By Climate Champions | October 23, 2023 Latin American and Caribbean Climate Week (LACCW) opens in Panama City today aiming to galvanize the LAC community around a common vision of what it takes to transition to a net zero emissions, nature-positive and resilient world. With just over one month to go until COP28, LAC CW,…

Abstract Groundwater is the physically largest freshwater ecosystem, yet one of the least explored habitats on earth, both because of accessing difficulties and the scarcity of the organisms inhabiting it. Here, we demonstrate how a two-fold approach provides complementary information on the occurrence and diversity of groundwater amphipods. Firstly, we used a citizen science approach…