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Carl Sagan’s audacious search for life on Earth has lessons for science today
Planetary scientist and broadcaster Carl Sagan, who died in 1996, influenced some of NASA’s planetary missions.Credit: Science History Images/Alamy Early in 1993, a manuscript landed in the Nature offices announcing the results of an unusual — even audacious — experiment. The investigators, led by planetary scientist and broadcaster Carl Sagan, had searched for evidence of…
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Meet the unsung scientists behind the Nobel for quantum dots
Nobel prizewinners almost never work in isolation. They might be the driving force behind their award-winning discoveries, but a whole host of collaborators, postdoctoral fellows and graduate students helped to realize their vision in the laboratory. Where do those scientists end up? What is it like for them to be part of a celebrated piece…
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Prognostic visualization model for primary pulmonary sarcoma: a SEER-based study
Abstract Primary pulmonary sarcoma (PPS) is a rare and poor prognostic malignancy that results from current clinical studies are lacking. Our study aimed to investigate the prognostic factors of PPS and to construct a predictive nomogram that predict the overall survival (OS) rate. We extracted data on patients diagnosed with PPS from 2010 to 2019…
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Correlation analysis of obesity phenotypes with leptin and adiponectin
Abstract Obesity can be categorized as metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUO). However, individuals with MHO are characterized by the absence of metabolic syndrome (MS) and appear to have lower inflammation levels compared to MUO. This study aimed to investigate the association of obesity phenotypes with leptin (LEP) and adiponectin (ADP). According…
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Physician–scientist trainees with parenting responsibilities need financial and childcare support
Physician–scientists who become parents during their long period of training need additional funding and support for lactation, childcare and healthcare, to ensure an equitable workforce. This is a preview of subscription content, access via your institution Access options Access through your institution Change institution Buy or subscribe /* style specs start */ style{display:none!important}.LiveAreaSection-193358632 *{align-content:stretch;align-items:stretch;align-self:auto;animation-delay:0s;animation-direction:normal;animation-duration:0s;animation-fill-mode:none;animation-iteration-count:1;animation-name:none;animation-play-state:running;animation-timing-function:ease;azimuth:center;backface-visibility:visible;background-attachment:scroll;background-blend-mode:normal;background-clip:borderBox;background-color:transparent;background-image:none;background-origin:paddingBox;background-position:0 0;background-repeat:repeat;background-size:auto…
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Deep asleep? You can still follow simple commands, study finds
Sleep studies often involve measuring the electrical activity in a person’s brain using electroencephalography.Credit: Getty Scientists once considered sleep to be like a shade getting drawn over a window between the brain and the outside world: when the shade is closed, the brain stops reacting to outside stimuli. A study published on 12 October in…
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Long COVID research risks losing momentum – we need a moonshot
COVID-19 offers researchers their best chance yet to understand, and find treatments for, a chronic illness associated with an infectious disease. Infection-associated chronic conditions are not widely understood. Partly because of this, people who develop such conditions often face scepticism and stigma; health-care systems are ill-equipped to deal with them; and cases are likely to…
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AI-powered structure-based drug design inspired by the lock-and-key model
Inspired by the classic lock-and-key model and advances in equivariant deep network design, we present a structure-based drug design model, SurfGen, which uses two types of equivariant graph neural networks to learn on protein surfaces and geometric structures to directly design small-molecule drugs. This is a preview of subscription content, access via your institution Access…
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Science is under threat in Argentina — we must call out the danger
Argentina goes to the polls on 22 October to elect a new president. Scientists, including me, are deeply concerned: there is a very real prospect that the candidate of the far-right Libertarian Party, Javier Milei, could be our country’s next leader. Argentinian presidents have far-reaching powers. They are both head of state and head of…
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Science is under threat in Argentina — we must call out the danger
Argentina goes to the polls on 22 October to elect a new president. Scientists, including me, are deeply concerned: there is a very real prospect that the candidate of the far-right Libertarian Party, Javier Milei, could be our country’s next leader. Argentinian presidents have far-reaching powers. They are both head of state and head of…