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How understudied endometriosis causes pain for hundreds of millions of women
Many women live with endometriosis but scientists say research into the condition is underfunded.Credit: GARO/PHANIE/Science Photo Library Pain-sensing nerves and immune cells work together to wreak havoc in endometriosis, a painful condition that affects an estimated 190 million women and girls of reproductive age. But a study in mice suggests a way to harness that…
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Trump’s US election win: researchers must stay strong and united
Moving on: Donald Trump’s re-election poses challenges for science.Credit: Loren Elliott/Getty When Donald Trump was first elected to the US presidency in 2016, Nature advised scientists to constructively engage with Trump. We said that the incoming president’s contrary approach to evidence, among other things, had no place in modern society. We added that the science…
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Citizen scientists can be chemists — give them a chance
What do the brain map of the fruit fly, the location of exoplanet WASP-77 A b, the identification of antibiotic resistance in the bacterium Escherichia coli and crop security of the cassava plant (Manihot esculenta) in Uganda have in common? They are all the subjects of breakthroughs made possible by citizen scientists. Members of the…
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Deep generative design of RNA aptamers using structural predictions
Abstract RNAs represent a class of programmable biomolecules capable of performing diverse biological functions. Recent studies have developed accurate RNA three-dimensional structure prediction methods, which may enable new RNAs to be designed in a structure-guided manner. Here, we develop a structure-to-sequence deep learning platform for the de novo generative design of RNA aptamers. We show…
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Science communication will benefit from research integrity standards
An anti-vaccination protester in New York City. Researchers are aiming to improve public trust in science by discussing uncertainty in their communications.Credit: Michael Nigro/Pacific Press/LightRocket/Getty “Twenty seconds, professor, and no long words.” This is what a BBC producer once told Ian Fells, a chemical engineer at Newcastle University, UK, shortly before Fells was due to…
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The antibodies don’t work! The race to rid labs of molecules that ruin experiments
Carl Laflamme knew what protein he wanted to study, but not where to find it. It is encoded by a gene called C9ORF72, which is mutated in some people with the devastating neurological condition motor neuron disease, also known as amyotrophic lateral sclerosis. And Laflamme wanted to understand its role in the disease. When he…
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Daily briefing: Heart attacks trigger deep healing sleep
Hello Nature readers, would you like to get this Briefing in your inbox free every day? Sign up here. Soon-to-be US president Donald Trump (left) and his vice-president, J.D. Vance, at an election night watch party.Credit: Evan Vucci/AP Photo/Alamy ‘We need to be ready for a new world’ Owing to Donald Trump’s anti-science rhetoric and…
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‘We need to be ready for a new world’: scientists globally react to Trump election
Soon-to-be US president Donald Trump (left) and his vice-president, J.D. Vance, at an election night watch party.Credit: Evan Vucci/AP Photo/Alamy Scientists around the world expressed disappointment and alarm as Republican Donald Trump won the final votes needed to secure the US presidency in the early hours of 6 November. Owing to Trump’s anti-science rhetoric and…
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When the Magic in Science, Nature, and Words Creates The Best Part of Us
The following article was written by author, Sally Cole-Misch. Join Wisconsin Sea Grant’s Titus Seilheimer in conversation with Sally Cole-Misch, author of Great Lakes, Great Read’s Adult Selection, “The Best Part of Us,” on Monday, November 11, at Manitowoc Public Library’s Balkansky Community Room from 6-7:30 PM I’ve always believed that words are magical. Strung…
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Nature Journal Chooses Politics Over Science
Mid adult male scientist reading scientific data in a laboratory. Does anyone else see the irony in the Nature journal editors proclaiming to defend science while blatantly endorsing political candidates? Todd Myers from the Washington Policy Center joins me as we break down how these so-called champions of scientific integrity only seem to care about…