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Identification of CXCL16 as a diagnostic biomarker for obesity and intervertebral disc degeneration based on machine learning
Abstract Intervertebral disc degeneration (IDD) is the primary cause of neck and back pain. Obesity has been established as a significant risk factor for IDD. The objective of this study was to explore the molecular mechanisms affecting obesity and IDD by identifying the overlapping crosstalk genes associated with both conditions. The identification of specific diagnostic…
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Identification of CXCL16 as a diagnostic biomarker for obesity and intervertebral disc degeneration based on machine learning
Abstract Intervertebral disc degeneration (IDD) is the primary cause of neck and back pain. Obesity has been established as a significant risk factor for IDD. The objective of this study was to explore the molecular mechanisms affecting obesity and IDD by identifying the overlapping crosstalk genes associated with both conditions. The identification of specific diagnostic…
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The forgotten D of DEI
To mark the United Nations International Day of Persons with Disabilities we have launched a collection on chemists with disabilities. Within diversity, equity and inclusion (DEI) efforts in science, this is a topic that is often overlooked. Since 1992, the United Nations has designated 3 December as the International Day of Persons with Disabilities. This…
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Risk factors for arteriovenous fistula dysfunction in hemodialysis patients: a retrospective study
Abstract Arteriovenous fistula (AVF) is the first choice of vascular access in hemodialysis (HD) patients. However, the correlations between patient factors and the arteriovenous fistula patency remain unclear. Therefore, our study investigates the risk factors associated with AVF dysfunction in HD patients. A total of 233 end-stage renal disease (ESDR) patients who met the study…
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Meteorites Were A Likely Source Of Nitrogen For Early Earth
a, Backscattered electron image of a fine Ryugu grain. The white boxes correspond to the areas shown in b and c. b, Secondary electron image of framboidal magnetite showing granular texture. c, Secondary electron image of porous iron sulfide surrounded by phyllosilicate. The arrow points to an iron whisker on the iron sulfide surface. Sample…
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What happens when nature and cities overlap
Editor’s note: A version of this story appeared in CNN’s Wonder Theory science newsletter. To get it in your inbox, sign up for free here. CNN — More than half of the world’s population live in urban areas where nature can feel like a distant concern. Thriving ecosystems do, however, exist within our cities — even…
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Why Mexico Wants You to Virtually Adopt an Axolotl Salamander
It can regenerate bits of its body. Ancient Mexicans revered it as a mischievous, shape-shifting god. They named it axolotl — translation: “water monster” — and it’s a “salamander with a Mona Lisa smile,” reports the Washington Post, “an alien-looking creature with a permanent grin and a crown of feathery gills”. But while there’s over…
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Kishida Says Japan Will Not Construct New Coal Power Plants at COP28
APPrime Minister Fumio Kishida delivers his speech during a COP28 meeting in Dubai on Friday. By Hirotaka Kuriyama / Yomiuri Shimbun Staff Writer 17:01 JST, December 2, 2023 DUBAI — Prime Minister Fumio Kishida said Japan will not build any new coal-fired power plants that do not have greenhouse gas emission reduction measures in place during…
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COP28: Earth’s frozen zones are in trouble – we’re already seeing the consequences
As this year’s UN climate summit (COP28) gets under way in Dubai, scientists studying Earth’s frozen regions have been delivering an urgent call for action to policy makers. But is anyone listening? Throughout 2023, we have been warning of an impending series of crises occurring in the cryosphere – polar ice sheets, ice shelves, sea…
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COP28: Earth’s frozen zones are in trouble – we’re already seeing the consequences
As this year’s UN climate summit (COP28) gets under way in Dubai, scientists studying Earth’s frozen regions have been delivering an urgent call for action to policy makers. But is anyone listening? Throughout 2023, we have been warning of an impending series of crises occurring in the cryosphere – polar ice sheets, ice shelves, sea…