The entertainment industry has questions to answer in light of allegations against comedian Russell Brand, Foreign Secretary James Cleverly has said.

Brand has been accused of rape and sexual assault in an investigation by Channel 4, the Times and Sunday Times.

He denied the allegations, and said his relationships were “always consensual”.

Mr Cleverly told the BBC those in power must “be better” at listening to the voices of the “relatively powerless”.

He told BBC One’s Sunday with Laura Kuenssberg: “I think there are some real challenges where you have these very, very acute differentials in power, whether that be in the entertainment industry, whether that be in politics, and we see this in the commercial world as well.

“I think we have to be particularly careful when we listen to the voices of the people who are relatively powerless because we, I think collectively, have missed opportunities to do the right thing and intervene much, much earlier, and we’ve got to be better at this.”

Asked whether there are questions for the industry, Mr Cleverly replied: “Sadly, I think there are.”

Meanwhile, the Trevi Women & Children’s Charity said it had cut ties with the comedian and had been “deeply saddened and upset” following the allegations.

In the investigation, four women accused Brand of sexual assaults between 2006 and 2013.

During those years, the star had various high-profile jobs at different times, including at BBC Radio 2 and Channel 4, and as being an actor in Hollywood films.

Author Irvine Welsh, also speaking on Kuenssberg’s programme, said every organisation in the entertainment industry “has to get its house in order so people do feel comfortable and it’s an environment where they can come forward and can be listened to”.

But things have “changed for the better” in recent years since the start of the Me Too movement, he added.

Other claims made in the investigation relate to Brand’s allegedly controlling, abusive and predatory behaviour.

Sunday Times media editor Rosamund Urwin, who worked on the story, told BBC Radio 4’s Broadcasting House there were “a lot of questions to be answered” by TV companies.

She said: “I think in the coming days we will see a lot more scrutiny, including in our paper, of who knew what when, and why on earth this man was continuing to go on Channel 4 shows as late as 2018/2019 when there certainly were widespread rumours that would have at least needed investigating before you put him on your channel.”

Within hours of the allegations being published, Brand performed a scheduled comedy gig at the 2,000-capacity Troubadour Wembley Park Theatre in north-west London.

During the set, which lasted about an hour, Brand alluded to the accusations but did not address them directly. He told the audience there were things he wanted to talk about but could not.

On Friday, Brand released a video in which he denied “serious criminal allegations” he said were about to be made against him.

The actor and comedian said he had received letters from a TV company and newspaper, containing “a litany” of “aggressive attacks”.

In the video, Brand said: “Amidst this litany of astonishing, rather baroque attacks are some very serious allegations that I absolutely refute.

“These allegations pertain to the time when I was working in the mainstream, when I was in the newspapers all the time, when I was in the movies, and as I’ve written about extensively in my books I was very, very promiscuous.

“Now during that time of promiscuity the relationships I had were absolutely, always consensual.”

Brand said he believed he was the subject of a “co-ordinated attack” and he was going to look into the matter because it was “very, very serious”.

While not referring to the comedian by name, the Metropolitan Police said it was “aware of media reporting of a series of allegations of sexual assault” but had not received any direct reports.

“If anyone believes they have been the victim of a sexual assault, no matter how long ago it happened, we would encourage them to contact police.”

One woman known as Alice told Channel 4’s Dispatches and the Sunday Times that Brand assaulted her when he was in his early 30s and she was 16 and still at school.

She said she took her allegations to his literary agent Angharad Wood, the co-founder of Tavistock Wood, owned by Curtis Brown, in 2020. But she said she received a “very aggressive” legal letter in response.

Tavistock Wood told the BBC: “Russell Brand categorically and vehemently denied the allegation made in 2020, but we now believe we were horribly misled by him. Tavistock Wood has terminated all professional ties to Brand.”

The Sunday Times reported that Alice later went to work for Channel 4 and raised concerns about his behaviour with the broadcaster in 2013 or 14.

The paper also said TV researchers and runners who worked on Channel 4 shows alleged that Brand would get staff to approach young female audience members, some of whom later contacted them in tears after feeling they had been treated poorly by Brand.

One researcher said Brand’s alleged behaviour was reported to managers at production company Endemol, which made programmes for Channel 4. The company told the paper it could find no record of problems being raised formally or discussed.

A Channel 4 spokesman told BBC News: “Channel 4 is appalled to learn of these deeply troubling allegations, including behaviour alleged to have taken place on programmes made for Channel 4 between 2004 and 2007.

“We are determined to understand the full nature of what went on. We have carried out extensive document searches and have found no evidence to suggest the alleged incidents were brought to the attention of Channel 4.”

The relationship with the 16-year-old is alleged to have taken place at a time when Brand was working as a presenter on BBC Radio 6 Music.

It is also alleged Brand would undress in the studio while working on the show. Dispatches also said Brand made a series of sexual remarks on air about a newsreader, which he later implied he had been told by BBC production staff to apologise for.

The Times added sources had told the newspaper that a complaint was made to BBC management about an “alarming display of aggression and disrespect” from Brand.

Urwin told Radio 4: “There was a level of controversy around everything he did, but we have these allegations of what went on at the BBC that seem completely and utterly inappropriate for a workplace, and were inappropriate for 2006 too.”

A BBC spokesman said: “Russell Brand worked for a number of different organisations, of which the BBC was one. As is well known, Russell Brand left the BBC after a serious editorial breach in 2008 – as did the then-controller of Radio 2.

“The circumstances of the breach were reviewed in detail at the time. We hope that demonstrates that the BBC takes issues seriously and is prepared to act.

“Indeed, the BBC has, over successive years, evolved its approach to how it manages talent and how it deals with complaints or issues raised.”

The corporation added that it had “clear expectations around conduct at work” and would “always listen to people if they come forward with any concerns, on any issue related to any individual working at the BBC, past or present”.