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Rams 37, Cardinals 14
GLENDALE, Ariz. — Matthew Stafford threw for 229 yards and a season-high four touchdown passes, two each to Tyler Higbee and Kyren Williams, and the Los Angeles Rams rolled to a win over the Arizona Cardinals. Williams had a huge game in his return from an ankle injury, running for 143 yards and catching six passes for 61 yards, including touchdown receptions of 15 and 3 yards. The Rams won their second straight game overall and continued their recent dominance in the NFC West rivalry, winning nine straight games in Arizona going back to 2014. Arizona quarterback Kyler Murray completed 27 of 45 passes for 256 yards and a touchdown in his third game since returning from an ACL tear in his right knee.
Chiefs 31, Raiders 17
LAS VEGAS — The Las Vegas Raiders squandered a 14-point lead and head into their bye week after a disappointing loss to the Kansas City Chiefs. Las Vegas was outscored 31-3 after taking an early 14-0 lead. The Chiefs scored 21 unanswered points to seize control of the game, and never looked back. The loss dropped the Raiders to 2-2 under interim coach Antonio Pierce since taking over for fired Josh McDaniels.
Broncos 27, Browns 12
DENVER — The Denver Broncos came up with a trio of takeaways in their win over the Cleveland Browns.
That gives the Broncos 15 takeaways in their last four games. They haven’t had that good of a stretch since 34 years. Russell Wilson ran for a score and threw for a touchdown in leading the Broncos to their fifth straight victory. The Browns fell to 7-4 as they managed just one touchdown and two field goals.
Jaguars 24, Texans 21
HOUSTON — Trevor Lawrence threw for 364 yards and a touchdown, and the AFC South-leading Jacksonville Jaguars escaped with a victory over the division rival Houston Texans. Houston had a chance to tie it with 34 seconds left, but Matt Ammendola’s 58-yard field goal attempt bounced off the crossbar. The Jaguars improved to 8-3, avenging their 37-17 home loss to Houston in Week 3 and creating some separation in the division. The Texans fell to 6-5. C.J. Stroud threw for 304 yards and two touchdowns for the Texans, whose three-game winning streak was snapped.
Titans 17, Panthers 10
NASHVILLE, Tenn. — Derrick Henry ran for two touchdowns and 76 yards helping the Tennessee Titans snap a three-game skid beating the Carolina Panthers. This was just the fourth game in Music City this season for the Titans, who played at home only once over the past seven weeks. Tennessee improved to 4-0 when playing at Nissan Stadium this season. Arden Key had a sack and forced fumble recovered by two-time Pro Bowl defensive lineman Jeffery Simmons. The Panthers remain winless away from home and have lost four straight.
Colts 27, Bucs 20
INDIANAPOLIS — Jonathan Taylor ran for two scores, Gardner Minshew added another and the Indianapolis Colts defense came up with a late turnover to preserve a 27-20 victory over Tampa Bay. Indy has won three straight to climb above .500 for the first time since the end of September. The Bucs have lost four straight road games, this one in uncharacteristic fashion.
Falcons 24, Saints 15
ATLANTA — Desmond Ridder overcame two interceptions by throwing a touchdown pass to Bijan Robinson in the fourth quarter and the Atlanta Falcons moved into a first-place tie in the woeful NFC South by beating the New Orleans Saints. The Saints and Falcons each are 5-6. The Saints were limited by injury problems at wide receiver after losing Chris Olave (concussion) and Rashid Shaheed (thigh). New Orleans still outgained the Falcons 444-397 as Derek Carr passed for 304 yards but had to settle for five field goals by Blake Grupe. Robinson ran for 91 yards with a touchdown.
Giants 10, Patriots 7
EAST RUTHERFORD, N.J. — Xavier McKinney set up Randy Bullock’s go-ahead 42-yard field goal midway through the fourth quarter with New York’s third interception of New England’s woeful pair of quarterbacks, and the Giants won consecutive games for the first time this season, beating the Patriots. New England had a chance to win in the final minute, but coach Bill Belichick played for a tie and Chad Ryland was wide left on a 35-yard field goal attempt with 3 seconds left. Tommy DeVito threw a touchdown pass for New York, which did more than enough against quarterbacks Mac Jones and Bailey Zappe to send the Patriots to their fourth straight loss.
Ravens 20, Chargers 10
INGLEWOOD, Calif. — Rookie Zay Flowers had a touchdown catch and ran for a game-sealing score late in the fourth quarter, Baltimore’s defense forced four turnovers, and the AFC-best Ravens beat the Los Angeles Chargers. Lamar Jackson threw for 177 yards and ran for 39 on 11 carries, becoming the fourth quarterback in NFL history to exceed 5,000 rushing yards — and the fastest by far to do it. Jackson has played 82 games, 22 fewer than it took Michael Vick to top 5,000.
The Chargers largely bottled up Jackson and the Ravens’ offense in the second half, but Flowers put the game away when he took an end-around on third-and-2 and dashed for a 37-yard touchdown with 1:36 left. Baltimore (9-3) heads into its bye week one-half game ahead of Kansas City, Jacksonville and Miami for the best record in the conference.
Justin Herbert was 29 of 44 for 217 yards with a touchdown and an interception for the Chargers (4-7) who have lost three straight.