More than 100 years since the X-ray was discovered, Philips is introducing an innovation to healthcare imaging. LumiGuide, powered by Fiber Optic RealShape (FORS) technology, enables doctors to navigate through blood vessels using light, instead of X-ray.
“[It’s] one of the most exciting changes that we’ve seen with imaging certainly throughout my career,” said Andres Schanzer, vascular surgeon, at UMass Memorial Medical Center, Worcester, MA, USA.
In late 2023, LumiGuide was used for the first time to treat patients in Maastricht University Medical Center in the Netherlands, closely followed by the University of Alabama at Birmingham in the USA. Developed in close collaboration with clinical partners, LumiGuide is made available, in first instance, to major Aortic Centers of Excellence that perform complex aortic repairs in the USA and Europe.
LumiGuide’s radiation-free technology brings potentially game-changing benefits for complex aortic procedures. In vascular surgery, physicians often perform endovascular surgery using devices like guidewires and catheters, via, for example, the femoral artery. This is also referred to as an endovascular procedure. For many decades clinicians had to only rely on x-ray to guide their devices through blood vessels. But x-ray can do both harm as well as good. In addition to its potentially harmful radiation, x-ray can only produce 2D black and white images. With physicians increasingly tackling far more complex endovascular procedures – such as aortic aneurysm repair – cases take more time, resulting in a higher radiation dose for patients and clinicians.
LumiGuide uses light reflected along an optical fibre inside a guidewire to generate 3D, high-resolution, colour images of devices, including off-the-shelf catheters, inside a patient’s body in real time, from any angle and in multiple views. It means that physicians know which direction their device is facing and can see where they need to go. This navigation can be done all without X-ray.
Dr. Atul Gupta, chief medical officer for Image Guided Therapy and Precision Diagnosis at Philips and practicing interventional radiologist, said: “If we can see more, we can proceed more quickly and more confidently. In effect, LumiGuide is a 3D human GPS system powered by light.”
Having worked on this technology for the past years, Philips has been able to already yield promising study results around the world. Following a limited release to nine aortic centres, more than 900 patients have undergone procedures – with one site, conducting a historic cohort comparison, showing a 37% reduction in complex aortic procedure time, and a 56% reduction in radiation exposure (DAP) compared to X-ray.
LumiGuide, which works exclusively with compatible Philips interventional systems like Azurion, is the second-generation solution to use FORS. Building on insights, data and clinical feedback from the first-generation devices used at the nine centres, LumiGuide includes new time-saving features. Instead of doctors having to manually register their devices with their image-guided therapy platform, LumiGuide uses AI-based recognition to register the guidewire, aiming to increase accuracy while speeding up procedure time even more. All the doctor needs to do is confirm the wire’s registration.
Prof. Geert Willem Schurink, vascular surgeon at Maastricht University Medical Center, who performed the first surgical procedure with LumiGuide, said: “This AI-based semi-automatic registration is very quick and accurate, even in the presence of stent grafts. Especially, if there is a need to re-register the device being guided in the patient’s body during the procedure, it is extremely helpful.”
As a next step, LumiGuide will enable Philips and clinical partners to gather more clinical data on the performance at existing sites in preparation of making the solution available globally.