Isoflavones are a plant form of estrogens found predominantly in soy products. A study published in Advances in Nutrition reviewed 40 clinical trials, including 3,285 post-menopausal women, and found that soy isoflavones did not have a negative effect on estrogen-related changes such as endometrial thickness, vaginal health, and hormone levels compared to placebos.1 In a recent study, the combination of a low-fat vegan diet and half a cup of soybeans daily led to an 88% reduction in moderate-to-severe hot flashes in menopausal women.2