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The decomposition of perturbation modeling

A recent study proposes a strategy for the prediction of genetic perturbation outcomes by breaking it down into three subtasks: identifying differentially expressed genes, determining expression change directions, and estimating gene expression magnitudes.

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Fig. 1: Overview of the STAMP conceptual framework for subtask decomposition of genetic perturbation response prediction.

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  1. European Molecular Biology Laboratory, Genome Biology, Heidelberg, Germany

    Stefan Peidli

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  1. Stefan Peidli
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Stefan Peidli.

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S.P. consults for Relation Therapeutics.

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Peidli, S. The decomposition of perturbation modeling.
Nat Comput Sci (2024). https://doi.org/10.1038/s43588-024-00706-4

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  • Published: 14 October 2024

  • DOI: https://doi.org/10.1038/s43588-024-00706-4

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