Proteomic scores and dietary patterns


Proteomic signatures associated with healthy dietary patterns can link diets to disease outcomes. Yet, it is unclear what information can be obtained through the development of proteomic signatures, how they can be used to elucidate the mechanisms linking dietary patterns to disease outcomes and whether they have utility in predicting and preventing diet-related diseases.

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References

  1. Zhu, K. et al. Nat. Food https://doi.org/10.1038/s43016-024-01059-x (2024).

    Article 
    PubMed 

    Google Scholar 

  2. Carrasco-Zanini, J. et al. Nat. Med. 30, 2489–2498 (2024).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  3. Carrasco-Zanini, J., Pietzner, M. & Langenberg, C. Curr. Diab. Rep. 20, 60 (2020).

    Article 

    Google Scholar 

  4. Pietzner, M. et al. Nat. Commun. 12, 6822 (2021).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  5. Li, C. et al. Am. J. Clin. Nutr. 116, 511–522 (2022).

    Article 
    ADS 
    PubMed 
    PubMed Central 

    Google Scholar 

  6. Sobiecki, J. G. et al. PLoS Med. 20, e1004221 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

Download references

Acknowledgements

N.J.W. is supported by the Medical Research Council (MC_UU_00006/1).

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Wareham, N.J. Proteomic scores and dietary patterns.
Nat Food (2024). https://doi.org/10.1038/s43016-024-01078-8

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  • Published: 12 November 2024

  • DOI: https://doi.org/10.1038/s43016-024-01078-8


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