Proteomic signatures associated with healthy dietary patterns can link diets to disease outcomes. Yet, it is unclear what information can be obtained through the development of proteomic signatures, how they can be used to elucidate the mechanisms linking dietary patterns to disease outcomes and whether they have utility in predicting and preventing diet-related diseases.
This is a preview of subscription content, access via your institution
Access options
/* style specs end */
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 digital issues and online access to articles
$119.00 per year
only $9.92 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
/* style specs start */
style {
display: none !important;
}
.LiveAreaSection * {
align-content: stretch;
align-items: stretch;
align-self: auto;
animation-delay: 0s;
animation-direction: normal;
animation-duration: 0s;
animation-fill-mode: none;
animation-iteration-count: 1;
animation-name: none;
animation-play-state: running;
animation-timing-function: ease;
azimuth: center;
backface-visibility: visible;
background-attachment: scroll;
background-blend-mode: normal;
background-clip: borderBox;
background-color: transparent;
background-image: none;
background-origin: paddingBox;
background-position: 0 0;
background-repeat: repeat;
background-size: auto auto;
block-size: auto;
border-block-end-color: currentcolor;
border-block-end-style: none;
border-block-end-width: medium;
border-block-start-color: currentcolor;
border-block-start-style: none;
border-block-start-width: medium;
border-bottom-color: currentcolor;
border-bottom-left-radius: 0;
border-bottom-right-radius: 0;
border-bottom-style: none;
border-bottom-width: medium;
border-collapse: separate;
border-image-outset: 0s;
border-image-repeat: stretch;
border-image-slice: 100%;
border-image-source: none;
border-image-width: 1;
border-inline-end-color: currentcolor;
border-inline-end-style: none;
border-inline-end-width: medium;
border-inline-start-color: currentcolor;
border-inline-start-style: none;
border-inline-start-width: medium;
border-left-color: currentcolor;
border-left-style: none;
border-left-width: medium;
border-right-color: currentcolor;
border-right-style: none;
border-right-width: medium;
border-spacing: 0;
border-top-color: currentcolor;
border-top-left-radius: 0;
border-top-right-radius: 0;
border-top-style: none;
border-top-width: medium;
bottom: auto;
box-decoration-break: slice;
box-shadow: none;
box-sizing: border-box;
break-after: auto;
break-before: auto;
break-inside: auto;
caption-side: top;
caret-color: auto;
clear: none;
clip: auto;
clip-path: none;
color: initial;
column-count: auto;
column-fill: balance;
column-gap: normal;
column-rule-color: currentcolor;
column-rule-style: none;
column-rule-width: medium;
column-span: none;
column-width: auto;
content: normal;
counter-increment: none;
counter-reset: none;
cursor: auto;
display: inline;
empty-cells: show;
filter: none;
flex-basis: auto;
flex-direction: row;
flex-grow: 0;
flex-shrink: 1;
flex-wrap: nowrap;
float: none;
font-family: initial;
font-feature-settings: normal;
font-kerning: auto;
font-language-override: normal;
font-size: medium;
font-size-adjust: none;
font-stretch: normal;
font-style: normal;
font-synthesis: weight style;
font-variant: normal;
font-variant-alternates: normal;
font-variant-caps: normal;
font-variant-east-asian: normal;
font-variant-ligatures: normal;
font-variant-numeric: normal;
font-variant-position: normal;
font-weight: 400;
grid-auto-columns: auto;
grid-auto-flow: row;
grid-auto-rows: auto;
grid-column-end: auto;
grid-column-gap: 0;
grid-column-start: auto;
grid-row-end: auto;
grid-row-gap: 0;
grid-row-start: auto;
grid-template-areas: none;
grid-template-columns: none;
grid-template-rows: none;
height: auto;
hyphens: manual;
image-orientation: 0deg;
image-rendering: auto;
image-resolution: 1dppx;
ime-mode: auto;
inline-size: auto;
isolation: auto;
justify-content: flexStart;
left: auto;
letter-spacing: normal;
line-break: auto;
line-height: normal;
list-style-image: none;
list-style-position: outside;
list-style-type: disc;
margin-block-end: 0;
margin-block-start: 0;
margin-bottom: 0;
margin-inline-end: 0;
margin-inline-start: 0;
margin-left: 0;
margin-right: 0;
margin-top: 0;
mask-clip: borderBox;
mask-composite: add;
mask-image: none;
mask-mode: matchSource;
mask-origin: borderBox;
mask-position: 0 0;
mask-repeat: repeat;
mask-size: auto;
mask-type: luminance;
max-height: none;
max-width: none;
min-block-size: 0;
min-height: 0;
min-inline-size: 0;
min-width: 0;
mix-blend-mode: normal;
object-fit: fill;
object-position: 50% 50%;
offset-block-end: auto;
offset-block-start: auto;
offset-inline-end: auto;
offset-inline-start: auto;
opacity: 1;
order: 0;
orphans: 2;
outline-color: initial;
outline-offset: 0;
outline-style: none;
outline-width: medium;
overflow: visible;
overflow-wrap: normal;
overflow-x: visible;
overflow-y: visible;
padding-block-end: 0;
padding-block-start: 0;
padding-bottom: 0;
padding-inline-end: 0;
padding-inline-start: 0;
padding-left: 0;
padding-right: 0;
padding-top: 0;
page-break-after: auto;
page-break-before: auto;
page-break-inside: auto;
perspective: none;
perspective-origin: 50% 50%;
pointer-events: auto;
position: static;
quotes: initial;
resize: none;
right: auto;
ruby-align: spaceAround;
ruby-merge: separate;
ruby-position: over;
scroll-behavior: auto;
scroll-snap-coordinate: none;
scroll-snap-destination: 0 0;
scroll-snap-points-x: none;
scroll-snap-points-y: none;
scroll-snap-type: none;
shape-image-threshold: 0;
shape-margin: 0;
shape-outside: none;
tab-size: 8;
table-layout: auto;
text-align: initial;
text-align-last: auto;
text-combine-upright: none;
text-decoration-color: currentcolor;
text-decoration-line: none;
text-decoration-style: solid;
text-emphasis-color: currentcolor;
text-emphasis-position: over right;
text-emphasis-style: none;
text-indent: 0;
text-justify: auto;
text-orientation: mixed;
text-overflow: clip;
text-rendering: auto;
text-shadow: none;
text-transform: none;
text-underline-position: auto;
top: auto;
touch-action: auto;
transform: none;
transform-box: borderBox;
transform-origin: 50% 50%0;
transform-style: flat;
transition-delay: 0s;
transition-duration: 0s;
transition-property: all;
transition-timing-function: ease;
vertical-align: baseline;
visibility: visible;
white-space: normal;
widows: 2;
width: auto;
will-change: auto;
word-break: normal;
word-spacing: normal;
word-wrap: normal;
writing-mode: horizontalTb;
z-index: auto;
-webkit-appearance: none;
-moz-appearance: none;
-ms-appearance: none;
appearance: none;
margin: 0;
}
.LiveAreaSection {
width: 100%;
}
.LiveAreaSection .login-option-buybox {
display: block;
width: 100%;
font-size: 17px;
line-height: 30px;
color: #222;
padding-top: 30px;
font-family: Harding, Palatino, serif;
}
.LiveAreaSection .additional-access-options {
display: block;
font-weight: 700;
font-size: 17px;
line-height: 30px;
color: #222;
font-family: Harding, Palatino, serif;
}
.LiveAreaSection .additional-login > li:not(:first-child)::before {
transform: translateY(-50%);
content: “”;
height: 1rem;
position: absolute;
top: 50%;
left: 0;
border-left: 2px solid #999;
}
.LiveAreaSection .additional-login > li:not(:first-child) {
padding-left: 10px;
}
.LiveAreaSection .additional-login > li {
display: inline-block;
position: relative;
vertical-align: middle;
padding-right: 10px;
}
.BuyBoxSection {
display: flex;
flex-wrap: wrap;
flex: 1;
flex-direction: row-reverse;
margin: -30px -15px 0;
}
.BuyBoxSection .box-inner {
width: 100%;
height: 100%;
padding: 30px 5px;
display: flex;
flex-direction: column;
justify-content: space-between;
}
.BuyBoxSection p {
margin: 0;
}
.BuyBoxSection .readcube-buybox {
background-color: #f3f3f3;
flex-shrink: 1;
flex-grow: 1;
flex-basis: 255px;
background-clip: content-box;
padding: 0 15px;
margin-top: 30px;
}
.BuyBoxSection .subscribe-buybox {
background-color: #f3f3f3;
flex-shrink: 1;
flex-grow: 4;
flex-basis: 300px;
background-clip: content-box;
padding: 0 15px;
margin-top: 30px;
}
.BuyBoxSection .subscribe-buybox-nature-plus {
background-color: #f3f3f3;
flex-shrink: 1;
flex-grow: 4;
flex-basis: 100%;
background-clip: content-box;
padding: 0 15px;
margin-top: 30px;
}
.BuyBoxSection .title-readcube,
.BuyBoxSection .title-buybox {
display: block;
margin: 0;
margin-right: 10%;
margin-left: 10%;
font-size: 24px;
line-height: 32px;
color: #222;
text-align: center;
font-family: Harding, Palatino, serif;
}
.BuyBoxSection .title-asia-buybox {
display: block;
margin: 0;
margin-right: 5%;
margin-left: 5%;
font-size: 24px;
line-height: 32px;
color: #222;
text-align: center;
font-family: Harding, Palatino, serif;
}
.BuyBoxSection .asia-link,
.Link-328123652,
.Link-2926870917,
.Link-2291679238,
.Link-595459207 {
color: #069;
cursor: pointer;
text-decoration: none;
font-size: 1.05em;
font-family: -apple-system, BlinkMacSystemFont, “Segoe UI”, Roboto,
Oxygen-Sans, Ubuntu, Cantarell, “Helvetica Neue”, sans-serif;
line-height: 1.05em6;
}
.BuyBoxSection .access-readcube {
display: block;
margin: 0;
margin-right: 10%;
margin-left: 10%;
font-size: 14px;
color: #222;
padding-top: 10px;
text-align: center;
font-family: -apple-system, BlinkMacSystemFont, “Segoe UI”, Roboto,
Oxygen-Sans, Ubuntu, Cantarell, “Helvetica Neue”, sans-serif;
line-height: 20px;
}
.BuyBoxSection ul {
margin: 0;
}
.BuyBoxSection .link-usp {
display: list-item;
margin: 0;
margin-left: 20px;
padding-top: 6px;
list-style-position: inside;
}
.BuyBoxSection .link-usp span {
font-size: 14px;
color: #222;
font-family: -apple-system, BlinkMacSystemFont, “Segoe UI”, Roboto,
Oxygen-Sans, Ubuntu, Cantarell, “Helvetica Neue”, sans-serif;
line-height: 20px;
}
.BuyBoxSection .access-asia-buybox {
display: block;
margin: 0;
margin-right: 5%;
margin-left: 5%;
font-size: 14px;
color: #222;
padding-top: 10px;
text-align: center;
font-family: -apple-system, BlinkMacSystemFont, “Segoe UI”, Roboto,
Oxygen-Sans, Ubuntu, Cantarell, “Helvetica Neue”, sans-serif;
line-height: 20px;
}
.BuyBoxSection .access-buybox {
display: block;
margin: 0;
margin-right: 10%;
margin-left: 10%;
font-size: 14px;
color: #222;
opacity: 0.8px;
padding-top: 10px;
text-align: center;
font-family: -apple-system, BlinkMacSystemFont, “Segoe UI”, Roboto,
Oxygen-Sans, Ubuntu, Cantarell, “Helvetica Neue”, sans-serif;
line-height: 20px;
}
.BuyBoxSection .price-buybox {
display: block;
font-size: 30px;
color: #222;
font-family: -apple-system, BlinkMacSystemFont, “Segoe UI”, Roboto,
Oxygen-Sans, Ubuntu, Cantarell, “Helvetica Neue”, sans-serif;
padding-top: 30px;
text-align: center;
}
.BuyBoxSection .price-buybox-to {
display: block;
font-size: 30px;
color: #222;
font-family: -apple-system, BlinkMacSystemFont, “Segoe UI”, Roboto,
Oxygen-Sans, Ubuntu, Cantarell, “Helvetica Neue”, sans-serif;
text-align: center;
}
.BuyBoxSection .price-info-text {
font-size: 16px;
padding-right: 10px;
color: #222;
font-family: -apple-system, BlinkMacSystemFont, “Segoe UI”, Roboto,
Oxygen-Sans, Ubuntu, Cantarell, “Helvetica Neue”, sans-serif;
}
.BuyBoxSection .price-value {
font-size: 30px;
font-family: -apple-system, BlinkMacSystemFont, “Segoe UI”, Roboto,
Oxygen-Sans, Ubuntu, Cantarell, “Helvetica Neue”, sans-serif;
}
.BuyBoxSection .price-per-period {
font-family: -apple-system, BlinkMacSystemFont, “Segoe UI”, Roboto,
Oxygen-Sans, Ubuntu, Cantarell, “Helvetica Neue”, sans-serif;
}
.BuyBoxSection .price-from {
font-size: 14px;
padding-right: 10px;
color: #222;
font-family: -apple-system, BlinkMacSystemFont, “Segoe UI”, Roboto,
Oxygen-Sans, Ubuntu, Cantarell, “Helvetica Neue”, sans-serif;
line-height: 20px;
}
.BuyBoxSection .issue-buybox {
display: block;
font-size: 13px;
text-align: center;
color: #222;
font-family: -apple-system, BlinkMacSystemFont, “Segoe UI”, Roboto,
Oxygen-Sans, Ubuntu, Cantarell, “Helvetica Neue”, sans-serif;
line-height: 19px;
}
.BuyBoxSection .no-price-buybox {
display: block;
font-size: 13px;
line-height: 18px;
text-align: center;
padding-right: 10%;
padding-left: 10%;
padding-bottom: 20px;
padding-top: 30px;
color: #222;
font-family: -apple-system, BlinkMacSystemFont, “Segoe UI”, Roboto,
Oxygen-Sans, Ubuntu, Cantarell, “Helvetica Neue”, sans-serif;
}
.BuyBoxSection .vat-buybox {
display: block;
margin-top: 5px;
margin-right: 20%;
margin-left: 20%;
font-size: 11px;
color: #222;
padding-top: 10px;
padding-bottom: 15px;
text-align: center;
font-family: -apple-system, BlinkMacSystemFont, “Segoe UI”, Roboto,
Oxygen-Sans, Ubuntu, Cantarell, “Helvetica Neue”, sans-serif;
line-height: 17px;
}
.BuyBoxSection .tax-buybox {
display: block;
width: 100%;
color: #222;
padding: 20px 16px;
text-align: center;
font-family: -apple-system, BlinkMacSystemFont, “Segoe UI”, Roboto,
Oxygen-Sans, Ubuntu, Cantarell, “Helvetica Neue”, sans-serif;
line-height: NaNpx;
}
.BuyBoxSection .button-container {
display: flex;
padding-right: 20px;
padding-left: 20px;
justify-content: center;
}
.BuyBoxSection .button-container > * {
flex: 1px;
}
.BuyBoxSection .button-container > a:hover,
.Button-505204839:hover,
.Button-1078489254:hover,
.Button-2737859108:hover {
text-decoration: none;
}
.BuyBoxSection .btn-secondary {
background: #fff;
}
.BuyBoxSection .button-asia {
background: #069;
border: 1px solid #069;
border-radius: 0;
cursor: pointer;
display: block;
padding: 9px;
outline: 0;
text-align: center;
text-decoration: none;
min-width: 80px;
margin-top: 75px;
}
.BuyBoxSection .button-label-asia,
.ButtonLabel-3869432492,
.ButtonLabel-3296148077,
.ButtonLabel-1636778223 {
display: block;
color: #fff;
font-size: 17px;
line-height: 20px;
font-family: -apple-system, BlinkMacSystemFont, “Segoe UI”, Roboto,
Oxygen-Sans, Ubuntu, Cantarell, “Helvetica Neue”, sans-serif;
text-align: center;
text-decoration: none;
cursor: pointer;
}
.Button-505204839,
.Button-1078489254,
.Button-2737859108 {
background: #069;
border: 1px solid #069;
border-radius: 0;
cursor: pointer;
display: block;
padding: 9px;
outline: 0;
text-align: center;
text-decoration: none;
min-width: 80px;
max-width: 320px;
margin-top: 20px;
}
.Button-505204839 .btn-secondary-label,
.Button-1078489254 .btn-secondary-label,
.Button-2737859108 .btn-secondary-label {
color: #069;
}
.uList-2102244549 {
list-style: none;
padding: 0;
margin: 0;
}
/* style specs end */
References
-
Zhu, K. et al. Nat. Food https://doi.org/10.1038/s43016-024-01059-x (2024).
Google Scholar
-
Carrasco-Zanini, J. et al. Nat. Med. 30, 2489–2498 (2024).
Google Scholar
-
Carrasco-Zanini, J., Pietzner, M. & Langenberg, C. Curr. Diab. Rep. 20, 60 (2020).
Google Scholar
-
Pietzner, M. et al. Nat. Commun. 12, 6822 (2021).
Google Scholar
-
Li, C. et al. Am. J. Clin. Nutr. 116, 511–522 (2022).
Google Scholar
-
Sobiecki, J. G. et al. PLoS Med. 20, e1004221 (2023).
Google Scholar
Acknowledgements
N.J.W. is supported by the Medical Research Council (MC_UU_00006/1).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing interests.
Rights and permissions
Reprints and permissions
About this article
Cite this article
Wareham, N.J. Proteomic scores and dietary patterns.
Nat Food (2024). https://doi.org/10.1038/s43016-024-01078-8
-
Published: 12 November 2024
-
DOI: https://doi.org/10.1038/s43016-024-01078-8